I have a virus,malware, spyware, toseeka,shopica,safe guard popups,blocked antiviris. Can anyone help?

My computer has a virus, malware and spyware. when I go to google or yahoo searches it goes to a site called TOSEEKA and SHOPICA. I am getting pop ups from systems safe guard every few mins. I tryed everything. I have avast. It blocked avast I can not uninstall avast or even type in the word avast in the search without it being blocked. I am unable to down load antimalware from the geek police or anyother anti viris spyware even from cds off line on safe mode. What should I do? Please help.

use malwarebytes
download from https://www.cleverbridge.com/342/cookie?affiliate=2183&product=29945&redirectto=http://www.gt500.org/malwarebytes/mbam.jsp
install it then use the quick scan then just use the quick scan
here’s a tutorial on how to use it http://www.help2go.com/Tutorials/Protect_Your_PC/Malwarebytes_Anti-malware_Tutorial.html