Help with infected computer?

Does anyone know of a good sure thing bootable program to remove spyware, malware, virus on a infected computer. the computer boots to desktop and locks up, also get the restore active desktop. works only in safe mode and have tried ALL !! free online scanners. Please help.

Virus and Malware/Spyware/Adware Removal Guide

Microsoft How To Get Rid Of Malware Instructions

http://social.answers.microsoft.com/Forums/en-US/vistasecurity/thread/ba80504b-61f1-4d71-960f-b561798b7b42

How To Run Microsoft Malicious Software Removal Tool

http://www.pchell.com/virus/malicioussoftwareremovaltool.shtml

Vernalex.com removal Guide:

http://www.vernalex.com/guides/malware/quick.shtml

When Malwarebytes will not Run or Install see here-

http://www.bleepingcomputer.com/forums/lofiversion/index.php/t256941.html

or here-

http://en.community.dell.com/wikis/spyware_virus/how-to-install-and-run-malwarebytes-anti-malware.aspx

To Clean Up Computer/Free Tools
Ccleaner from- http://www.ccleaner.com/
screenshot- http://www.ccleaner.com/screenshots
ATF from- http://download.cnet.com/ATF-Cleaner/3000-18512_4-89432.html?tag=mncol

To stop this from happening again
Microsoft Security Essentials-

http://www.microsoft.com/security_essentials/default.aspx

Ranked as #2 overall

http://www.thewindowsclub.com/microsoft-security-essentials-ranked-no-2-out-of-25

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SOFTPEDIA 2008 Award – How to fix Slow Windows

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